Nicotine is a potent parasympathomimetic stimulant and an alkaloid found in the nightshade family of plants. Nicotine acts as an exogenous receptor agonist at most nicotinic acetylcholine receptors (nAChRs), except at two nicotinic receptor subunits (nAChRα9 and nAChRα10) where it acts as an exogenous receptor antagonist. Nicotine is found in the leaves of Nicotiana rustica, in amounts of 2–14%; in the tobacco plant, Nicotiana tabacum; in Duboisia hopwoodii; and in Asclepias syriaca.It constitutes approximately 0.6–3.0% of the dry weight of tobacco. Usually consistent concentrations of nicotine varying from 2–7 µg/kg (20–70 millionths of a percent wet weight) are found in the edible family Solanaceae, such as potatoes, tomatoes, and eggplant. Wikipedia

Substance Data

Source: TOXNET (HSDB, 22.01.2019)



Flash Point


Boiling Point


Emergency Response Guide No. 151

Data from the Hazardous Materials Table

Source: 49 CFR §172 (2018/07)

(3) Hazard Class

Poisonous Material

(4) Identification number Help

UN 1654

(5) Packing Group Help


(6) Labels Help

Poisonous liquids PG I Zone A (6.1)

(7) Special Provisions (§172.102) Help

Special provisions may be very complex. The extracts are taken from 49 CFR §172.102. Please be careful with the information, as necessary, additional conditions may be applied that are not written here. Please check the original source and report bugs.

(8) Packing Authorizations (§173.***) Help

(8A) Exceptions153see 49 CFR §173.153
(8B) Non-bulk202see 49 CFR §173.202
(8C) Bulk243see 49 CFR §173.243

(9) Quantity Limits Help

(9A) Passenger aircraft/rail5 L
(9B) Cargo aircraft only60 L

(10) Vessel stowage Help

(10A) Location
(10B) Other n/a

Segregation Chart for Load, Transport, Storage

In this table a statement is contained for each hazard class whether the loading, transport or storage with other hazard classes is allowed, is not permitted or is restricted. The table is based on U.S.-Code 49 CFR §177.848.

There are no restrictions with hazardous materials, as pointed out in the instructions for using the Segregation Table (see 49 CFR §177.848(e)). But please, refer to following requirements in 49 CFR §177 Subpart B (Loading and Unloading):
  • §177.834 - General requirements
  • §177.835 - Class 1 materials
  • §177.837 - Class 3 materials
  • §177.838 - Class 4 (flammable solid) materials, Class 5 (oxidizing) materials, and Division 4.2 (pyroforic liquid) materials.
  • §177.839 - Class 8 (corrosive) materials
  • §177.840 - Class 2 (gases) materials
  • §177.841 - Division 6.1 and Division 2.3 materials
  • §177.842 - Class 7 (radioactive) material
  • §177.843 - Contamination of vehicles.