HazMat Tool — substance information

Tris, bis-bifluoroamino diethoxy propane (TVOPA)

HMT May 2026

UN / ID: n/a
Hazard class: Forbidden
Packing group: —
ERG guide: —
Special provisions: —
Source: 49 CFR §172 (2026/05)

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Tris, bis-bifluoroamino diethoxy propane (TVOPA)

Tris, or tris(hydroxymethyl)aminomethane, or known during medical use as tromethamine or THAM, is an organic compound with the formula (HOCH2)3CNH2. It is extensively used in biochemistry and molecular biology as a component of buffer solutions such as in TAE and TBE buffers, especially for solutions of nucleic acids. It contains a primary amine and thus undergoes the reactions associated with typical amines, e.g., condensations with aldehydes. Tris also complexes with metal ions in solution. Wikipedia

Hazardous Materials Table

Source: 49 CFR §172 (2026/05)

(3) Hazard Class

Forbidden

(4) Identification number

n/a

(5) Packing Group

n/a

(6) Labels

n/a

(7) Special Provisions (§172.102)

(8) Packing Authorizations (§173.***)

(8A) Exceptions	n/a	see 49 CFR §173. n/a
(8B) Non-bulk	n/a	see 49 CFR §173. n/a
(8C) Bulk	n/a	see 49 CFR §173. n/a

(9) Quantity Limits

(9A) Passenger aircraft/rail	n/a
(9B) Cargo aircraft only	n/a

(10) Vessel stowage

(10A) Location	n/a see
(10B) Other	n/a

Segregation chart for load, transport, and storage

This chart shows whether loading, transport, or storage with other hazard classes is permitted, prohibited, or restricted. Based on 49 CFR §177.848.

This Hazmat is classified as "Forbidden". This means the material may not be offered for transportation or transported in the applicable mode of transport.