HazMat Tool — substance information
Hexafluoroacetone
HMT 15 June 2026- UN / ID
- UN 2420
- Hazard class
- 2.3
- Packing group
- n/a (multiple — see tabs)
- ERG guide
- ERG 125
- Special provisions
- SP 2, SP B9, SP B14
- Source
- 49 CFR §172 (15 June 2026)
Hexafluoroacetone
Hexafluoroacetone (HFA) is a chemical compound with the formula (CF3)2CO. It is structurally similar to acetone; however, its reactivity is markedly different. It is a colourless, hygroscopic, nonflammable, highly reactive gas characterized by a musty odour. According to electron diffraction, HFA and acetone adopt very similar structures, the C-O distance being only longer in the fluorinated compound (124.6 vs 121.0 pm), possibly due to steric effects. The term "hexafluoroacetone" can refer to the sesquihydrate (1.5 H2O), which is a hemihydrate of hexafluoropropane-2,2-diol (F3C)2C(OH)2, a geminal diol Wikipedia
| Emergency Response Guide No. 125 |
Hazardous Materials Table
Source: 49 CFR §172 (15 June 2026)(3) Hazard Class2.3Poisonous gas |
(4) Identification number |
(5) Packing Group |
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(6) Labels |
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(7) Special Provisions (§172.102)
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| 2 | |
|---|---|
| B9 | |
| B14 |
(8) Packing Authorizations (§173.***) 
| (8A) Exceptions | None | |
|---|---|---|
| (8B) Non-bulk | 304 | see 49 CFR §173.304 |
| (8C) Bulk | 314, 315 | see 49 CFR §173.314, 315 |
(9) Quantity Limits
| (9A) Passenger aircraft/rail | Forbidden |
|---|---|
| (9B) Cargo aircraft only | Forbidden |
(10) Vessel stowage
| (10A) Location | |
|---|---|
| (10B) Other |
(3) Hazard Class6.1Poisonous Material |
(4) Identification number |
(5) Packing Group |
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(6) Labels |
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(7) Special Provisions (§172.102)
|
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| IB8 | |
|---|---|
| IP2 | |
| IP4 | |
| T3 | |
| TP33 |
(8) Packing Authorizations (§173.***)
| (8A) Exceptions | 153 | see 49 CFR §173.153 |
|---|---|---|
| (8B) Non-bulk | 212 | see 49 CFR §173.212 |
| (8C) Bulk | 242 | see 49 CFR §173.242 |
(9) Quantity Limits
| (9A) Passenger aircraft/rail | 25 kg |
|---|---|
| (9B) Cargo aircraft only | 100 kg |
(10) Vessel stowage
| (10A) Location | |
|---|---|
| (10B) Other |
(3) Hazard Class3Flammable liquids |
(4) Identification number |
(5) Packing Group |
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(6) Labels |
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(7) Special Provisions (§172.102)
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| IB2 | |
|---|---|
| T4 | |
| TP1 | The maximum degree of filling must not exceed the degree of filling determined by the following:  Where: tr is the maximum mean bulk temperature during transport, and tf is the temperature in degrees celsius of the liquid during filling. |
(8) Packing Authorizations (§173.***)
| (8A) Exceptions | 150 | see 49 CFR §173.150 |
|---|---|---|
| (8B) Non-bulk | 202 | see 49 CFR §173.202 |
| (8C) Bulk | 242 | see 49 CFR §173.242 |
(9) Quantity Limits
| (9A) Passenger aircraft/rail | 5 L |
|---|---|
| (9B) Cargo aircraft only | 60 L |
(10) Vessel stowage
| (10A) Location | |
|---|---|
| (10B) Other | n/a |
(3) Hazard Class6.1Poisonous Material |
(4) Identification number |
(5) Packing Group |
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(6) Labels |
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(1) Symbols This entry is signed with plus (+). The plus (+) sign fixes the proper shipping name, hazard class and packing group for that entry without regard to whether the material meets the definition of that class, packing group or any other hazard class definition. When the plus sign is assigned, it means that the material is known to pose a risk to humans. When a plus sign is assigned to mixtures or solutions containing a material where the hazard to humans is significantly different from that of the pure material or where no hazard to humans is posed, the material may be described using an alternative shipping name that represents the hazards posed by the material. An appropriate alternate proper shipping name and hazard class may be authorized by the Associate Administrator. |
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| 2 | |
|---|---|
| T20 | |
| TP2 | a. The maximum degree of filling must not exceed the degree of filling determined by the following:  Where: tr is the maximum mean bulk temperature during transport, tf is the temperature in degrees celsius of the liquid during filling, and α is the mean coefficient of cubical expansion of the liquid between the mean temperature of the liquid during filling (tf) and the maximum mean bulk temperature during transportation (tr) both in degrees celsius. b. For liquids transported under ambient conditions α may be calculated using the formula:  Where: d15 and d50 are the densities (in units of mass per unit volume) of the liquid at 15 °C (59 °F) and 50 °C (122 °F), respectively. |
| TP13 |
(8) Packing Authorizations (§173.***)
| (8A) Exceptions | None | |
|---|---|---|
| (8B) Non-bulk | 193 | see 49 CFR §173.193 |
| (8C) Bulk | 245 | see 49 CFR §173.245 |
(9) Quantity Limits
| (9A) Passenger aircraft/rail | Forbidden |
|---|---|
| (9B) Cargo aircraft only | Forbidden |
(10) Vessel stowage
| (10A) Location | |
|---|---|
| (10B) Other |
(3) Hazard Class6.1Poisonous Material |
(4) Identification number |
(5) Packing Group |
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(6) Labels |
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(7) Special Provisions (§172.102)
|
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| IB3 | |
|---|---|
| T4 | |
| TP1 | The maximum degree of filling must not exceed the degree of filling determined by the following: Where: tr is the maximum mean bulk temperature during transport, and tf is the temperature in degrees celsius of the liquid during filling. |
(8) Packing Authorizations (§173.***)
| (8A) Exceptions | 153 | see 49 CFR §173.153 |
|---|---|---|
| (8B) Non-bulk | 203 | see 49 CFR §173.203 |
| (8C) Bulk | 241 | see 49 CFR §173.241 |
(9) Quantity Limits
| (9A) Passenger aircraft/rail | 60 L |
|---|---|
| (9B) Cargo aircraft only | 220 L |
(10) Vessel stowage
| (10A) Location | |
|---|---|
| (10B) Other |
Packing group comparison
Multiple packing groups apply to this entry. See assignment criteria in 49 CFR §173 Subpart D. Details are in the tabs above; differences are highlighted.
| PG n/a | PG II | PG II | PG II | PG III | |
|---|---|---|---|---|---|
| 1 | + | ||||
| 2 | Hexafluoroacetone | 1,3-Dichloroacetone | Acetone | Bromoacetone | Hexachloroacetone |
| 3 | 2.3 | 6.1 | 3 | 6.1 | 6.1 |
| 4 | UN 2420 | UN 2649 | UN 1090 | UN 1569 | UN 2661 |
| 5 | n/a | II | II | II | III |
| 6 | 2.3, 8 | 6.1 | 3 | 6.1, 3 | 6.1 |
| 7 | 2, B9, B14 | IB8, IP2, IP4, T3, TP33 | IB2, T4, TP1 | 2, T20, TP2, TP13 | IB3, T4, TP1 |
| 8A | None | 153 | 150 | None | 153 |
| 8B | 304 | 212 | 202 | 193 | 203 |
| 8C | 314, 315 | 242 | 242 | 245 | 241 |
| 9A | Forbidden | 25 kg | 5 L | Forbidden | 60 L |
| 9B | Forbidden | 100 kg | 60 L | Forbidden | 220 L |
| 10A | D | B | B | D | B |
| 10B | 40 | 12, 25, 40 | n/a | 40 | 12, 40 |
Segregation chart for load, transport, and storage
This chart shows whether loading, transport, or storage with other hazard classes is permitted, prohibited, or restricted. Based on 49 CFR §177.848.
Note: The HMR prohibit only those Division 6.1 liquids that meet the definition of a Packing Group (PG) I and Hazard Zone A. See special provision 1 and PHMSA Interpretation #09-0252.
Packages with POISON or POISON INHALATION HAZARD labels, or a POISON label displaying “PG III,” or “PG III” marked next to a POISON label may not be transported with foodstuffs, feed or any other edible material, intended for humans or animals. For exceptions see 49 CFR §177.841(e).
Scope & sources (important)Click to show CFR references
This check evaluates segregation per 49 CFR §177.848. Additional loading/unloading and handling requirements may still apply; see 49 CFR §177 Subpart B (Loading and Unloading):
- §177.834 - General requirements
- §177.835 - Class 1 materials
- §177.837 - Class 3 materials
- §177.838 - Class 4 (flammable solid) materials, Class 5 (oxidizing) materials, and Division 4.2 (pyroforic liquid) materials
- §177.839 - Class 8 (corrosive) materials
- §177.840 - Class 2 (gases) materials
- §177.841 - Division 6.1 and Division 2.3 materials
- §177.842 - Class 7 (radioactive) material
- §177.843 - Contamination of vehicles